Cost-effective encapsulation of active agents or drugs to be released against pollution, corrosion, or medical condition.

OFFER from France, reference: TOFR20181121001, valid from 22-11-2018 untill 24-11-2019

  • Title:
    Cost-effective encapsulation of active agents or drugs to be released against pollution, corrosion, or medical condition.
  • Start date:
    22 november 2018
  • End date:
    24 november 2019
  • Summary:
    An innovative process for the synthesis of Layered Double Hydroxide (LDH) is ready to be transfered. Its simple and energy-saving protocol can customize LDH which includes active agents to be released for pollutant extraction, corrosion inhibition, or drug delivery. A French Technology Transfer Office (TTO) is looking for a licensing agreement or a technical cooperation agreement with companies dealing with polluted site clean-up products, anti-corrosion coatings, or drugs encapsulation.
  • Description:
    A new process for the synthesis of Layered Double Hydroxide (LDH) has been designed as a cost-saving and efficient encapsulation of active agents. Moreover, it allows to customize materials or chemical preparations to be released against pollution, corrosion, or medical condition.
    It has been set up and patented by a French research team which is represented by a Technology Transfer Office (TTO) for its industrial partnership and industrial property management.

    Market challenges :
    LDHs have a broad range of applications in catalysis, electrochemistry, biomedical and environmental sciences. In particular, LDHs can be used for anion exchange and anion extraction processes and as a controlled release drug or phytochemicals delivery systems.
    Current LDH synthesis method requires a complex protocol and high energetic cost. In addition, they have a limited range of applications.

    State of the art :
    LDHs are widely used as acidity regulators. Moreover, they have got interesting properties such as a large specific surface area, which is very useful for heterogenous catalysis. As an example, it has been tested for biodiesel synthesis. Until now, the only LDH available on the market is Mg-Al carbonate hydrotalcite.
    There are other promising use cases for LDHs such as pollutant capture or drug delivery. Nevertheless, there is no simple, efficient and cheap method to prepare customized LDHs dedicated to those applications. Especially, there is a strong need for a cost-effective method of anion extraction from a medium (e.g. to depollute or recycle a substance).

    Proposed technology :
    The patented technology consists in a new process for exchanging interlayer anions of LDH with other anions whose affinity for the LDH is lower than the one of the initial interlayer anions.
    This method allows the preparation of customized LDH for extracting anions from a liquid medium (with a following step to regenerate the LDH).
    As compared to the synthesis of Mg-Al carbonate hydrotalcite which is the only one available on the market, the patented process is efficient and cost-effective for the extraction of any metal or any pollutant in liquid medium. It can also be applied to drug controlled release for human or vegetal health treatment.

    Requested partner :
    Manufacturers or end-user companies dealing with pollutant capture, corrosion inhibition, or even drug delivery are requested for either a licensing agreement, or a technical cooperation agreement on a specific usecase.

    Keywords :
    Layered Double Hydroxide, aqueous solution metal extraction, recycling, depollution, encapsulation, drug vectorisation.
Partner Sought
  • Type of Partnership Considered:
    License agreement, Technical cooperation agreement
  • Technical Specification or Expertise Sought:

    The requested partner may be a company interested in the controlled release of active agents to be used for pollutant capture, corrosion inhibition, or even sustained drug release.
    Expected outcomes are either :

    - a licensing agreement prior to an industrial development of an innovative product based on the proposed technology, or

    - a technical cooperation agreement in order to set up a customized LDH for a specific use case in any of the following application fields : pollution, corrosion, drug vectorisation for health or plant cultivation.

    SME 11-50,SME <10,>500 MNE,251-500,SME 51-250,>500

  • Development stage:
    Available for demonstration
  • IPR Status:
    Patents granted
  • Market keywords:
    Drug delivery and other equipment
    Plant health
    Chemical and solid material recycling
    Other pollution and recycling related
  • Technology keywords:
    Other Processes
    Micro- and Nanotechnology
  • NACE keywords:
    Other research and experimental development on natural sciences and engineering
  • Advantages and Innovations:
    The innovative encapsulation process can be implemented in a continuous way, and can use as a starting point any LDH, including the commercially available Mg-Al carbonate hydrotalcite.

    The proposed technology allows an easy access to LDHs with various types of interlayer anions e.g. drug, biomolecule, catalyst, anti-corrosive agent, depending on the application considered :

    - Environment : depollution, recycling, extraction in liquid medium of critical and strategic metals from electronic waste,
    - Paint industries : encapsulation of anionic active substance in paints as corrosion inhibitor,
    - Pharmaceutical industries : encapsulation of drugs e.g. ibuprofen,
    - Phytosanitary industries : encapsulation of herbicids e.g. picloram.

  • Type and Size of Organisation:
    Industry SME 11-49
  • Already Engaged in Trans-National Cooperation
  • Year Established:
  • Turnover:
  • Country of origin:
  • Languages spoken
    • English
    • French