Title:Eurostars: partners sought to develop the next generation biomaterials for the prevention of infections within the healthcare sector
- Technology profile
- REQUEST from United Kingdom, reference: RDUK20160617001, valid from 23-06-2016 untill 27-06-2017
Created:28 juni 2016
Updated:29 juni 2016
Profile typeResearch & Development request
Country of origin:United Kingdom
Start date:23 juni 2016
End date:27 juni 2017
Technologic information profile
Description:A SME specialising in the development of next generation biomaterials for the prevention of infections within the healthcare sector seeks collaborative partners. The SME has extensive experience in the development of photo-initiated polymers and microbiology and have carried out several R&D projects leading to early stage commercialisation interest. Their platform technology has a wide range of potential applications and they are working with household name strategic partners in the United Kingdom and other countries.
There is an urgent clinical need for solutions to the problem of infections caused by the formation of biofilms (bacteria films) in or on medical devices. These infections are becoming more antibiotic resistance and alternative treatments are needed to reduce healthcare induced infections.
The SME’s technology platform is concerned with the application of photo-initiated polymer materials integrated into urinary catheters to minimize the formation of biofilms and reduce or eliminate the probability of infections induced by the use of standard catheters. The application of photo-initiated polymers for application to catheters thus has the potential to improve the quality of patient care and reduce the significant cost of corrective treatments due to infections or blockages on or in the catheter. Urinary catheters are the number one cause of infections in healthcare. This typically costs healthcare providers on average £2,000-3,000 per patient/per year in corrective care and treatment (£125M/per year in the UK alone).
Revenues in the US and European urological device sector were $4.7 billion in 2013, whilst the global urological catheters market is forecast to exceed $3.0 Billion by 2017.
There is a market need for catheters incorporating some form of antimicrobial property to offer both an improvement in patient care and the reduction in cost of patient care by the elimination or minimisation of infection and blockages caused by biofilm formation on the catheter surface. Alternate markets for this antimicrobial platform technology include the global instrumentation market which is forecast to surpass US$56 billion by the year 2017, driven by an ageing population, rising incidence of age-related conditions and improved surgical procedures.
Proof of principal of the technology has been proven and the development of the technology from TRL3 to TRL6 is required to further develop the commercial proposition and establish a prototype to strengthen market interest and begin to establish a route to market.
The project objectives will be focus on extending the lifetime of the photo-initiated polymer materials and improving the efficacy of the antimicrobial material to extend the time-period a blockage free urinary catheter can be maintained such that long-term patient use is possible.
Most studies have indicated that optimal biofilm and blockage prevention is most effectively achieved by interaction and prevention at the surface of the catheter. The SMEs technology platform achieves this by novel surface treatment of the polymer surface for photo-initiated activation so minimising biofilm formation and reducing the likelihood of blockage or infection once inserted into the patient’s bladder.
The company is searching for EU SME’s or research organisations preferably in Scandinavia or the Netherlands with expertise in molecular modelling, testing of polymers, testing drug release systems as the coordinator lacks such expertise and these are one of the few requirements of this projects
Call Deadline- 15 Sept 2016
EoI Deadline- 05 Aug 2016
Project Duration - 2 Years
- Medcine, Human Health
- Biology / Biotechnology
- Other research and experimental development on natural sciences and engineering
Plus Value:The characteristics of the final product and material will be
• A photo initiated polymer that becomes antimicrobial when activated by light
• Increase lifetime of the baseline antimicrobial host polymers and antimicrobial specific to species
IPR Status:Patents granted
Type of organisation:
Type and Size:Industry SME = 10
Technical Specification or Expertise Sought:pInterested partners should be able to perform at least one of the following task:
- Molecular modelling
- Development of photo initiated materials
- Microbiological testing
- Building and running urinary bladder test systems
- Biofilm production testingppThe organisation/s should have experience in molecular modelling, testing of polymers, testing drug release systems, microbiological testing of biofilms and a capability to develop an artificial bladder system for antimicrobial material testing.
The SME is also interested in collaborative partners with a knowledge of catheters to establish clear requirements for material and production scenarios. ppSME 11-50,University,R&D Institution,SME 10,500 MNE,251-500,SME 51-250,500p
- Research cooperation agreement
Deadline:15 september 2016
Evaluation:International innovative project led by R&D-performing SMEs
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